angerous than the actual smallpox virus. Healthcare providers administered it using a bifurcated needle, which was dipped into the vaccine solution and then used to make multiple tiny punctures into the superficial layer of the skin, known as the dermis. This deliberate, controlled injury was designed to stimulate the immune system to produce protective antibodies.
Once the virus entered the dermis,…
Once the virus entered the dermis, it multiplied and triggered a localized immune response. This process manifested as a small raised bump, which evolved into a fluid filled blister
