8 Early Warning Signs of Nerve Changes That Often Begin in Your Toes

fatigue worse during the day.

If symptoms regularly wake you up, it is worth discussing them with a healthcare professional.

## What Can Cause Nerve Problems?

Nerve symptoms can have many possible causes.

Common ones include:

* diabetes
* vitamin B12 deficiency
* excessive vitamin B6 supplementation
* thyroid disease
* kidney disease
* alcohol misuse
* chemotherapy
* certain medications
* autoimmune conditions
* nerve compression
* spinal disc problems
* infections
* physical injury

Sometimes no obvious cause is identified.

Anatomy

## Diabetes Is a Major Cause

Persistently high blood sugar can damage nerves over time.

Diabetic peripheral neuropathy often begins in the feet and may cause:

* numbness
* tingling
* burning
* pain
* reduced ability to feel heat or injury

Good blood glucose management can help reduce the risk of further nerve damage.

##  Vitamin B12 Deficiency Can Affect Nerves

Vitamin B12 is important for maintaining healthy nerve cells.

Blood Sugar & Diabetes

A deficiency can cause:

tingling
* numbness
* weakness
* balance problems
* fatigue
* memory or concentration

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